T. B. Merkulova

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2-Arylamino-6-methylnicotinic Acid Alkylamides (V-XIII). A solution of 0.01 mole of the 2-chloro-6-methylnicotinic acid alkylamide and 0.01 mole of the arylamine in 20 ml of 50% acetic acid was boiled for 6 h, cooled, and neutralized with a 10% solution of sodium hydroxide. The precipitate which separated was filtered off and recrystallized from a mixture(More)
5-Aminomethyl-2-methyl-3-phen~lindole (IX).. A suspension of 36.6 g (0.1 mole) of 5phthalimidomethyl-2-methyl-3-methylindole in 800 ml of methanol and 16.7 ml of hydrazine hydrate are heated on the water bath until completely dissolved and the solution then refluxed for 3 hours. After cooling, excess dilute HCI (i:i) is added and the precipitate filtered(More)
The synthesis and antimicrobial activity of 4,7-dihydroand 4,5,6,7-tetrahydroisoindoles have been reported earlier [i]. In a continuation of the investigation of the biological properties of this new class of compounds, we have hydrogenated a series of 4,5,6,7tetrahydroisoindoles and studied the pharmacological activity of several of the hydrogenated(More)
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