Tânia Margarida Lourenço

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Mesenchymal stem cells (MSCs) are viewed as safe, readily available and promising adult stem cells, which are currently used in several clinical trials. Additionally, their soluble-factor secretion and multi-lineage differentiation capacities place MSCs in the forefront of stem cell types with expected near-future clinical applications. In the present work(More)
Extracellular matrix (ECM) proteins play a key role during oligodendrogenesis. While fibronectin (FN) is involved in the maintenance and proliferation of oligodendrocyte progenitor cells (OPCs), merosin (MN) promotes differentiation into oligodendrocytes (OLs). Mechanical properties of the ECM also seem to affect OL differentiation, hence this study aimed(More)
OBJECTIVE To compare the effectiveness and risk profile of minimally invasive interventions against the current standard of transurethral resection of the prostate. DESIGN Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES Electronic and paper records up to March 2006. REVIEW METHODS We searched for all relevant(More)
Oligodendrocytes (OLs) are responsible for the myelination of axons in the central nervous system (CNS). The differentiation of OLs encompasses several stages, through which cells undergo dramatic biochemical and morphological changes. OL differentiation is modulated by soluble factors (SFs)-such as growth factors and hormones-, known to be essential for(More)
The purpose of this study was to describe and compare the reproductive success and egg and larvae quality between wild and first-generation (F1) breeders of Argyrosomus regius. Wild broodstock were adapted to captivity, and good-quality spawns were obtained in 2009–2010, after GnRH treatment. In 2012, the F1 meagre (3 years old) spawned naturally at IPMA’s(More)
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