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BACKGROUND The current evidence on effect of fluoridation in drinking water on bone is inconsistent. This study was undertaken to assess the effect of fluoride concentration in drinking water on bone mineral density (BMD) in Taiwanese women. METHODS The study subjects included 248 women aged > or = 40 years who reside in naturally fluoridated and adjacent(More)
This presentation describes the application of novel high throughput physical-chemical technologies to the pharmaceutical discovery and development process. The rationale for such platforms is described in light of the changes that have occurred in the biological and chemical processes leading to drug target evaluation and lead identification. Several high(More)
AIM To study the manifestations of perihepatic lymph nodes during the episode of acute hepatitis flare by point-of-care ultrasonography. METHODS One hundred and seventy-six patients with an episode of acute hepatitis flare (ALT value > 5 × upper normal limit) were enrolled retrospectively. Diagnosis of etiology of the acute hepatitis flare was based on(More)
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