Szilard Voros

Learn More
Coronary computed tomography angiography (CTA) allows coronary artery visualization and the detection of coronary stenoses. In addition; it has been suggested as a novel, noninvasive modality for coronary atherosclerotic plaque detection, characterization, and quantification. Emerging data show that coronary CTA-based semiquantitative plaque(More)
OBJECTIVES This study sought to determine the accuracy of 3-dimensional, quantitative measurements of coronary plaque by computed tomography angiography (CTA) against intravascular ultrasound with radiofrequency backscatter analysis (IVUS/VH). BACKGROUND Quantitative, 3-dimensional coronary CTA plaque measurements have not been validated against IVUS/VH.(More)
Most acute coronary syndromes are caused by sudden luminal thrombosis due to atherosclerotic plaque rupture or erosion. Preventing such an event seems to be the only effective strategy to reduce mortality and morbidity of coronary heart disease. Coronary lesions prone to rupture have a distinct morphology compared with stable plaques, and provide a unique(More)
BACKGROUND Numerous studies have compared coronary CT angiography (CTA) with quantitative coronary angiography. However, the ability of coronary CTA to identify atherosclerosis and to accurately measure plaque and coronary area and volume measurements as compared with intravascular ultrasound (IVUS) has not been fully defined. OBJECTIVE We sought to(More)
BACKGROUND CAC has been used to predict obstructive CAD on invasive coronary angiography. However, it is unknown how the prevalence of obstructive CAD in patients with zero CAC is influenced by the presence or absence of chest pain. METHODS 210 consecutive patients referred for CAC and CorCTA were included in this analysis. Chest pain was defined based on(More)
BACKGROUND Currently available noninvasive tests to risk stratify patients for obstructive coronary disease result in many unnecessary cardiac catheterizations, especially in women. We sought to compare the diagnostic accuracy of presenting symptoms, noninvasive test results, and a gene expression score (GES) in identifying obstructive coronary artery(More)
he study by Henneman et al. (1) included 40 consecutive patients ith suspected acute coronary syndrome who underwent coronary rtery calcium (CAC) scoring and computed tomography coronary ngiography. Of the entire cohort of 40 patients, 5 had obstructive isease and no presence of CAC. The authors concluded that in his cohort absence of CAC does not reliably(More)
The objective of this study was to compare the diagnostic accuracy of quantitative coronary angiography (QCA), coronary computed tomography angiography (CTA), and intravascular ultrasound (IVUS) with fractional flow reserve (FFR) measurements. Eighty-five lesions (40% to 99% diameter stenosis) in 85 patients were prospectively interrogated by QCA, CTA,(More)
OBJECTIVES This study was designed to assess the effects on resource utilization of routine coronary computed tomographic angiography (CCTA) in triaging chest pain patients in the emergency department (ED). BACKGROUND The routine use of CCTA for ED evaluation of chest pain is feasible and safe. METHODS We conducted a retrospective multivariate analysis(More)
Alterations in gene expression in peripheral blood cells have been shown to be sensitive to the presence and extent of coronary artery disease (CAD). A non-invasive blood test that could reliably assess obstructive CAD likelihood would have diagnostic utility. Microarray analysis of RNA samples from a 195 patient Duke CATHGEN registry case:control cohort(More)