Syunsuke Demizu

Learn More
BACKGROUND Patched 1 (Ptc1) is a polytopic receptor protein that is essential for growth and differentiation. Its extracellular domains accept its ligand, Sonic Hedgehog, while the function of its C-terminal intracellular domain is largely obscure. PRINCIPAL FINDINGS In this study, we stably expressed human Ptc1 protein in HeLa cells and found that it is(More)
  • 1