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PURPOSE Reanalysis after a 5-year follow-up previously presented relationships between spontaneous and radiation-induced micronucleus frequencies in tumour cells and the clinical outcome of patients with advanced stages (II B-IV B) of cervix carcinomas treated with radiotherapy. MATERIALS AND METHODS Spontaneous and induced in vitro and in vivo(More)
In an effort to find a test to predict the response of normal tissue to radiotherapy, the lymphocyte micronucleus assay was used on blood samples from patients with cervical carcinoma. Peripheral blood samples from 55 patients with advanced-stage (II B-IV B) cervical carcinoma were obtained before radiotherapy. The patients were treated with external-beam(More)
A potential usefulness of micronucleus assay for prediction of tumour radiosensitivity has been tested in 64 patients with advanced stage (II B-IV B) cervical carcinoma treated by radiotherapy. The study of cellular radiosensitivity in vitro was conducted in parallel with the study of cellular damage after tumour irradiation in vivo. Radiosensitivity of in(More)
A retrospective study of all patients with carcinoma of the vulva treated by surgery and/or radiation therapy, between 1980 and 1985, is reported. Sixty eight patients were analyzed for survival, recurrence patterns, complications and clinical features. The stages of disease were as follows: Stage I or II 49 pts, Stage III 13 pts and Stage IV 6 pts. The(More)
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