Sylvie Bonin-Guillaume

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To compensate for poor acute pain detection in elderly inpatients with inability to communicate verbally (ICV), the Doloplus Collective team devised the 5-item Algoplus behavior-assessment scale specifically aimed at quickly detecting acute pain in these individuals. Algoplus was developed in three successive phases, including expert opinions, caregivers(More)
Apathy and depression are the most frequent neuropsychiatric symptoms in Alzheimer's disease (AD). In a cross-sectional observational study of 734 subjects with probable mild AD, we evaluated the prevalence of apathy and depression. After the use of specific diagnostic criteria, we tested the interaction between the two syndromes and their relation with(More)
An epidemiology closely linked with the increase in life span. In most countries, the prevalence of dementia varies between 6 and 8% for individuals aged 65 years or more. It then dramatically increases with each subsequent decade, reaching around 30% of the population aged over 85. The costs associated with dementia are correlated with the increase in age(More)
Psychomotor retardation (PMR) is a main symptom of depressive illness. In the elderly, it is associated with the severity of depression and poor prognosis. However, PMR is also commonly associated with normal aging, Therefore, depressive PMR is frequently misinterpreted as the age-related slowing in the elderly, which contributes to poor recognition of(More)
UNLABELLED BACKGROUND/STUDY CONTEXT: No emotion-induction procedure is clearly recommended to assess the emotional reactivity in the elderly. This study aimed to validate an emotional reactivity procedure in healthy old patients. METHODS Nineteen healthy elders (age range: 66-91 years old) were compared with 19 education- and sex-matched young adults (age(More)
OBJECTIVES Validation in the elderly of the Retardation Rating Scale (RRS), which includes items related to motor and mental retardation but not vegetative items, and may be particularly well-suited for the diagnosis of depression in the elderly. METHODS One hundred and sixty-five geriatric inpatients (105 depressed), aged 65 and over, without dementia,(More)
OBJECTIVES Driving is an important part of everyday life for the elderly today. Older drivers are suspected to be involved in more automobile accidents than younger adults. Although healthcare professionals are aware of specific diseases and impairments that increase accident risks, they cannot distinguish safe from unsafe drivers among the healthy elderly(More)
OBJECTIVES To identify independent risk factors of mortality among elderly patients in the 3 months after their visit (T3) to an emergency department (ED). DESIGN Prospective cohort study. SETTING University hospital ED in an urban setting in France. PARTICIPANTS One hundred seventy-three patients aged 75 and older were admitted to the ED over two(More)
As a result of the development of neurodegenerative diseases our societies are faced with a major challenge. More than 850 000 people in France are affected by Alzheimer's disease or a related disorder. The huge impact of these diseases on the quality of life of the patients and their carers requires a concerted effort to provide high-quality support at(More)