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Type 2 diabetes frequently results from progressive failure of pancreatic beta-cell function in the presence of chronic insulin resistance. We tested whether chronic amelioration of insulin resistance would preserve pancreatic beta-cell function and delay or prevent the onset of type 2 diabetes in high-risk Hispanic women. Women with previous gestational(More)
OBJECTIVE This report presents national estimates and trends for a variety of oral health status measures for persons aged 2 years and older by sociodemographic and smoking status since the late 1980s in the United States. METHODS Data from the third National Health and Nutrition Examination Survey (NHANES III), 1988-1994 and from the NHANES 1999-2004(More)
OBJECTIVE To evaluate the immediate and long-term effects of 2 upper-extremity rehabilitation approaches for stroke compared with standard care in participants stratified by stroke severity. DESIGN Nonblinded, randomized controlled trial (baseline, postintervention, 9mo) design. SETTING Inpatient rehabilitation hospital and outpatient clinic. (More)
Although clinical coronary heart disease and many cardiovascular risk factors are well known to aggregate within families, the heritability of carotid artery intima-media thickness (IMT) is less well documented. We report IMT heritability estimates in Mexican American, Salvadoran American, or Guatemalan American (all referred to as Latino) families(More)
UNLABELLED This study sought to examine relationships between depressive symptoms and prenatal smoking and/or household environmental tobacco smoke exposure (HH-ETSE) among urban minority women. We analyzed private, audio computer-assisted self interview data from a clinic-based sample of 929 minority pregnant women in Washington, DC. Depressive symptoms(More)
OBJECTIVE To estimate the age- and gender-specific prevalence of early age-related macular degeneration (AMD; drusen and retinal pigmentary abnormalities) and advanced AMD (exudative AMD and geographic atrophy) in Latinos. DESIGN Population-based, cross-sectional study. PARTICIPANTS Six thousand three hundred fifty-seven Latinos 40 years and older from(More)
BACKGROUND We previously reported an association between prenatal cocaine exposure (PCE) and childhood behavior problems as observed by the parent or caretaker. However, these behavior problems may not manifest in a structured environment, such as a school setting. OBJECTIVE We determined whether there is an association between PCE and school behavior(More)
A total of 16 patients with recurrent epithelial ovarian cancer were treated with sulofenur (LY 186641), a novel oral sulfonylurea. All subjects had received previous chemotherapy. Anaemia occurred in all 16 patients, 14 of whom required a blood transfusion, and 2/16 patients received methylene blue for breathlessness due to methaemaglobinaemia. Treatment(More)
We measured human herpesvirus-8 antibodies (K8.1 and orf73 enzyme immunoassays) in 4166 children, aged 6-17 years, in a U.S. cross-sectional survey. Forty-six were K8.1 seropositive (weighted seroprevalence: 1.1%) and 20 were orf73 seropositive (weighted seroprevalence 0.4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence(More)
Recent research has suggested that depression causes teens to begin smoking to elevate their mood. Other studies, however, have suggested the reverse causal direction: smoking causes depression. To gain a more complete understanding of the relationship between smoking and depression, potential mediators should be explored. This study explored how peer(More)