Sylvain Dreifuss

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OBJECTIVE To determine the volumes of subcortical nuclei in patients with chronic epilepsy. BACKGROUND Animal and human data suggest a crucial role for subcortical structures in the modulation of seizure activity, mostly as seizure-suppressing relays. Although cortical epileptogenic foci can vary in localization and extent, it nevertheless appears that(More)
INTRODUCTION New therapeutic concepts in the management of ocular inflammation have led to the development of periocular and intravitreal injections. Such treatment modalities can induce intraocular pressure elevation. PATIENTS AND METHODS Periocular injections have been given to patients suffering from strictly unilateral or bilateral but asymmetrical(More)
A 68-year-old woman had uneventful deep sclerectomy with a collagen implant in the left eye that was complicated by infectious keratitis 2 weeks later. Corneal scraping revealed the presence of Staphylococcus aureus. The patient responded to topical antibiotic treatment, and the corneal infiltration resolved, leaving a corneal scar. Bacterial keratitis may(More)
PURPOSE The exact anatomic and neurophysiologic correlates of idiopathic generalized epilepsy (IGE) in humans are still not well understood, although the thalamus has frequently been invoked as the crucial structure in the generation of primary generalized seizures. The few in vivo magnetic resonance (MR)-based studies in IGE patients suggest an altered(More)
A nterior segment optical coherence tomography (OCT) is a noninvasive, painless, noncontact technique that provides accurate and reproducible images. This technique correlates well with ultrasound biomicroscopy, allows observation of iridocorneal angle abnormalities in the presence of opaque media, and is easier to perform than ultrasound biomicroscopy. A(More)
Rats that have drunk a concentrated glucose solution to satiety, and will drink no more of it if access is prolonged, will return to vigorous ingestion if offered carbohydrate powder or laboratory chow. We show that this specificity of satiety is maintained even if the initial glucose load is delivered directly to the stomach, bypassing the stimuli and the(More)
In food-deprived rats, rate of lapping at a saccharin cylinder declines progressively over a session. The decline is unaffected, within limits, by restricted access: Whether the cylinder is available continuously, or only during alternate 30-sec intervals, the rat adjusts its momentary lap rate so that the amount of lapping within each 5-min period remains(More)
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