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The eikonal equation and variants of it are of significant interest for problems in computer vision and image processing. It is the basis for continuous versions of mathematical morphology, stereo, shape-from-shading and for recent dynamic theories of shape. Its numerical simulation can be delicate, owing to the formation of singularities in the evolving… (More)

We present a fast, robust and automatic method for computing centerline paths through tubular structures for application to virtual endoscopy. The key idea is to utilize a skeletonization algorithm which exploits properties of the average outward flux of the gradient vector field of a Euclidean distance function from the boundary of the structure. The… (More)

We consider the use of medial surfaces to represent symmetries of 3-D objects. This allows for a qualitative abstraction based on a directed acyclic graph of components and also a degree of invariance to a variety of transformations including the articulation of parts. We demonstrate the use of this representation for 3-D object model retrieval. Our… (More)

We introduce an algorithm for segmenting brain magnetic resonance (MR) images into anatomical compartments such as the major tissue classes and neuro-anatomical structures of the gray matter. The algorithm is guided by prior information represented within a tree structure. The tree mirrors the hierarchy of anatomical structures and the subtrees correspond… (More)

The logarithm of the odds ratio (LogOdds) is frequently used in areas such as artificial neural networks, economics, and biology, as an alternative representation of probabilities. Here, we use LogOdds to place probabilistic atlases in a linear vector space. This representation has several useful properties for medical imaging. For example, it not only… (More)

- Jungsu S Oh, Marek Kubicki, Gudrun Rosenberger, Sylvain Bouix, James J Levitt, Robert W McCarley +2 others
- Human brain mapping
- 2009

Diffusion tensor imaging (DTI) and fiber tractography are useful tools for reconstructing white matter tracts (WMT) in the brain. Previous tractography studies have sought to segment reconstructed WMT into anatomical structures using several approaches, but quantification has been limited to extracting mean values of diffusion indices. Delineating WMT in… (More)

The eikonal equation and variants of it are of significant interest for problems in computer vision and image processing. It is the basis for continuous versions of mathematical morphology, stereo, shape-from-shading and for recent dynamic theories of shape. Its numerical simulation can be delicate, owing to the formation of singularities in the evolving… (More)

The medial surface of a volumetric object is of significant interest for shape analysis. However, its numerical computation can be subtle. Methods based on Voronoi techniques preserve the object's topo-logy, but heuristic pruning measures are introduced to remove unwanted faces. Approaches based on Euclidean distance functions can localize medial surface… (More)

- Motoaki Nakamura, Dean F Salisbury, Yoshio Hirayasu, Sylvain Bouix, Kilian M Pohl, Takeshi Yoshida +3 others
- Biological psychiatry
- 2007

BACKGROUND
Overall neocortical gray matter (NCGM) volume has not been studied in first-episode schizophrenia (FESZ) at first hospitalization or longitudinally to evaluate progression, nor has it been compared with first-episode affective psychosis (FEAFF).
METHODS
Expectation-maximization/atlas-based magnetic resonance imaging (MRI) tissue segmentation… (More)

- Aristotle N Voineskos, Nancy J Lobaugh, Sylvain Bouix, Tarek K Rajji, Dielle Miranda, James L Kennedy +3 others
- Brain : a journal of neurology
- 2010

In healthy adult individuals, late life is a dynamic time of change with respect to the microstructural integrity of white matter tracts. Yet, elderly individuals are generally excluded from diffusion tensor imaging studies in schizophrenia. Therefore, we examined microstructural integrity of frontotemporal and interhemispheric white matter tracts in… (More)