Sybil McAleese

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Scutate scales are completely missing in the scaleless (sc/sc) mutant chicken. Organ cultures consisting of epidermis from sc/sc embryos combined with normal (+/+) scale dermis of the same developmental age produce the scaleless phenotype, but the same scaleless epidermis in combination with normal dermis from more differentiated embryonic scales forms(More)
The gene for topoisomerase II has been isolated from genomic libraries of strain K1 of the human malarial parasite, Plasmodium falciparum. The sequence reveals an open reading frame of 4194 nucleotides which predicts a polypeptide of 1398 amino acids. There are apparently no introns. The sequence is present as a single copy which has an identity of 47.4%(More)
The gene encoding the malarial homologue of proliferating cell nuclear antigen, PCNA, has been identified and characterised. It is located on chromosome 13. The coding sequence of 825 nucleotides predicts a protein of 30,586 Da. There are no introns and northern analysis reveals a transcript of approximately 1.6kb. The conserved residues which characterise(More)
Morphogenesis of avian conjunctival papillae follows a predictable temporal and spatial pattern and is in some manner directly related to the introduction of the underlying scleral ossicles. We have been able, using Scanning Electron Microscopy (SEM), to correlate all of Murray's ('43) histological stages (1--6) of papillae development, with changes in(More)
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