Sybil Hirsch

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Acquired hemophilia A is a severe bleeding disorder caused by an autoantibody to factor VIII. Previous reports have focused on referral center patients and it is unclear whether these findings are generally applicable. To improve understanding of the disease, a 2-year observational study was established to identify and characterize the presenting features(More)
The aim of the present study was to validate a simple scoring system using a parent-completed screening questionnaire to identify children aged 5-15 yrs who may have asthma. A stratified random sample of 157 children of 1,808 whose parents had answered a postal respiratory questionnaire underwent detailed clinical evaluation. The results were reviewed by(More)
PURPOSE To use a neural network to rank a population according to individual likelihood of asthma based on their responses to a respiratory questionnaire. METHODS A final diagnosis of asthma can be made only after full clinical assessment but limited resources make it impossible to offer this to complete populations as part of a screening programme.(More)
Following in-patient psychiatric treatment under Section 3 of the Mental Health Act, some patients have in the past remained on Section after discharge, and subsequently the Section has been renewed while the patient remained 'on leave'. People treated thus with 'extended leave' probably resemble closely those who would be placed on a community treatment(More)
OBJECTIVE To investigate the effect of induced abortion on the outcome of the next pregnancy. DESIGN Long-term prospective controlled cohort study. SETTING Joint Royal College of General Practitioners/Royal College of Obstetricians and Gynaecologists study based in general practice in England, Scotland and Wales. SUBJECTS 1311 women whose recruitment(More)
BACKGROUND There has been little available information regarding secular changes in the prevalence of respiratory symptoms since the mid-1990s. AIM To examine changes in the prevalence of respiratory symptoms for 1993-2001. DESIGN OF STUDY A series of postal questionnaire surveys. SETTING Two general practice populations, including all age groups. (More)
BACKGROUND A large proportion of a general practitioner's (GP's) caseload comprises patients with mental health problems. It is important to ensure that care is provided appropriately, on the basis of clinical need. It is therefore necessary to investigate the determinants of the use of mental health care in the primary care sector and, in particular, to(More)
Several English consultant psychiatrists were asked to identify which patients currently under their care they would recommend for treatment with a community treatment order, if such a provision existed. The psychiatrists were asked to match each such 'nominated' patient for age, sex and diagnosis with one or two control patients, not considered to require(More)
BACKGROUND In 1998, the UK government published a White Paper in which it set long-term targets for reducing smoking in the population. This longitudinal study aimed to examine whether progress has been made in achieving these in two adult general practice populations over an 8-year period. METHODS Postal respiratory questionnaires, based on the European(More)