Sweta Kumari

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We have recently developed tert-dodecane S-nitrosothiol (tDodSNO) as a photoactivated nitric oxide (NO) donor. We here compare the potency of tDodSNO to S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylpenicillamine (SNAP), drugs which are also based upon the S-nitrosothiol functionality and have been extensively used for NO release studies.(More)
Cancer cell line selection serves as a milestone step for anti-cancer drug discovery. In this brief communication an attempt has been made to reviewed distinct human cancer (liver cancer, lung cancer, breast cancer, lymphoma, colon cancer, melanoma, leukemia, myeloma tumors, gastric cancer, promyelocytic leukemia, pancreatic adenocarcinoma, skin fibroblast(More)
Nitric oxide is a small messenger molecule utilized by nature in cell signalling and the non-specific immune response. At present, nitric oxide releasing prodrugs cannot be efficiently targeted towards a specific body compartment, which restricts their therapeutic applications. To address this limitation, we have designed two photolabile nitric oxide(More)
Dietary quality is an important limiting factor for proper nutrition in many resource poor settings, with a major concern, micronutrient bioavailability. High content of phytate present in soybean (Glycine max. L) chelates divalent essential mineral ions and reduces its bioavailability and thus dictates the nutritional role of this wonder crop. In this(More)
The nutritional benefits of soybean remain underutilized as the off-flavor present in it limits the consumption and acceptability among people. The aim of the present study was to unveil the effect of the phytohormones methyl jasmonate (MJ: 0, 50 μM, 1 mM, and 15 mM) and salicylic acid (SA: 0, 50 μM, 0.1 mM, and 10 mM) as elicitors on two contrasting(More)
γ-Tocopherol methyltransferase (γ-TMT) (EC 2.1.1.95) is the last enzyme in the tocopherol biosynthetic pathway and it catalyzes the conversion of γ-tocopherol into α-tocopherol, the nutritionally significant and most bioactive form of vitamin E. Although the γ-TMT gene has been successfully overexpressed in many crops to enhance their α-tocopherol content(More)
AIM To study the analgesic effect of oral 25% glucose as compared with oral 24% sucrose during heel lance in preterm neonates. METHODS Stable preterm neonates within first 48 hours of life were randomized to receive either 24% sucrose or 25% glucose before heel lance. Primary outcome assessed was painful response by the Premature Infant Pain Profile(More)
SQUAMOSA Promoter-Binding Protein-Like (SPL) genes form a major family of plant-specific transcription factors and play an important role in plant growth and development. In this study, we report the identification of 41 SPL genes (GmSPLs) in the soybean genome. Phylogenetic analysis revealed that these genes were divided into five groups (groups 1–5).(More)