Swati Singh

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The availability of complete genome sequences of H. pylori 26695 has provided a wealth of information enabling us to carry out in silico studies to identify new molecular targets for pharmaceutical treatment. In order to construe the structural and functional information of complete proteome, use of computational methods are more relevant since these(More)
  • Satya Brata Routh, Komal Ishwar Pawar, Sadeem Ahmad, Swati Singh, Katta Suma, Mantu Kumar +4 others
  • 2016
D-aminoacyl-tRNA deacylase (DTD) removes D-amino acids mischarged on tRNAs and is thus implicated in enforcing homochirality in proteins. Previously, we proposed that selective capture of D-aminoacyl-tRNA by DTD's invariant, cross-subunit Gly-cisPro motif forms the mechanistic basis for its enantioselectivity. We now show, using nuclear magnetic resonance(More)
An impedimetric mga gene specific DNA sensor was developed by immobilization of single stranded DNA probe onto the screen printed modified gold-dendrimer nanohybrid composite electrode for early and rapid detection of S. pyogenes in human throat swab samples causing rheumatic heart disease. Electrochemical impedance response was measured after hybridization(More)
Job shop scheduling problem is one of the most difficult NP-hard combinatorial optimization problems. Therefore, determining an optimal schedule and controlling and it is considered a difficult task. To achieve high performance in manufacturing firms, a scheduling system should make the right decision at the right time according to system conditions. It is(More)
World Wide Web presents challenging aspects or task for mining web data stream. Currently processing of useful data from web data stream is getting complex because when we considering the large volume of web log data it does not provide well-structured data. Two major challenge involved in web usage mining are processing the raw data to provide a (very(More)
Cold shock proteins (CSPs) have a widespread occurrence from prokaryotes to eukaryotes including plants. These proteins are known to possess nucleic acid binding properties. CSPs have a single cold shock domain in prokaryotes while N-terminal and C-terminal flanking regions are present in eukaryotic CSPs. The objective of this study was to investigate(More)
In the present investigation, we prepared and evaluated the paclitaxel loaded riboflavin and thiamine conjugated multi walled carbon nanotubes (PTX-Rf-MWCNTs and PTX-Tm-MWCNTs) for targeted delivery to cancer employing MCF-7 cancer cell lines. The developed conjugates were characterized using FTIR, NMR spectroscopy, electron microscopy drug loading,(More)
BACKGROUND The aim of this study was to report the outcomes of powered endoscopic dacryocystorhinostomy (PEnDCR) in patients with lacrimal sac within the sinus. MATERIALS AND METHODS Retrospective analysis was performed on all patients who underwent PEnDCR and were intraoperatively documented to have complete lacrimal sac in sinus. Data collected included(More)
BACKGROUND Palliative care is the proactive care which seeks to maximize quality of life for people and families facing life-threatening illnesses. OBJECTIVES To ascertain the existing knowledge of palliative care among medical interns and determine the effect of a structured educational intervention on improvement of their knowledge levels. SUBJECTS(More)