Swati Pande

  • Citations Per Year
Learn More
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust sequence-only methods have been developed. In this report, we demonstrate that three different feed forward neural networks, trained on a variety of sequence-based properties, can(More)
The variability within calculated protein residue pKa values calculated using Poisson-Boltzmann continuum theory with respect to small conformational fluctuations is investigated. As a general rule, sites buried in the protein core have the largest pKa fluctuations but the least amount of conformational variability; conversely, sites on the protein surface(More)
  • 1