Swati Gupta Bhattacharya

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Asthma is characterized by lung inflammation caused by complex interaction between the immune system and environmental factors such as allergens and inorganic pollutants. Recent research in this field is focused on discovering new biomarkers associated with asthma pathogenesis. This review illustrates updated research associating biomarkers of allergic(More)
BACKGROUND Mannose-binding Allium sativum leaf agglutinin (ASAL) is highly antinutritional and toxic to various phloem-feeding hemipteran insects. ASAL has been expressed in a number of agriculturally important crops to develop resistance against those insects. Awareness of the safety aspect of ASAL is absolutely essential for developing ASAL transgenic(More)
INTRODUCTION AND OBJECTIVES Pollen grains released by plants are dispersed into the air and can become trapped in human nasal mucosa, causing immediate release of allergens triggering severe Type 1 hypersensitivity reactions in susceptible allergic patients. Recent epidemiologic data show that 11-12% of people suffer from this type of disorders in India.(More)
In this chapter, five popular allergen databases have been described: (1) Allergome is based on basic and clinical information on allergens causing an IgE-mediated disease; (2) AllergenOnline allows online search of peer-reviewed allergen list; (3) International Union of Immunological Societies Allergen nomenclature subcommittee database contains systematic(More)
Allergy is a type of abnormal immune reactions, which is triggered by environmental antigens or allergens and mediated by IgE antibodies. Now-a-days mass spectrometry is the method of choice for allergen identification based on homology searching. Here, we provide the mass spectrometry dataset associated with our previously published research article on(More)
The worldwide prevalence of fungal allergy in recent years has augmented mining allergens from yet unexplored ones. Curvularia pallescens (CP) being a dominant aerospore in India and a major sensitiser on a wide range of allergic population, pose a serious threat to human health. Therefore, we aimed to identify novel allergens from CP in our present study.(More)
Currently, the prediction of new allergens is becoming important due to use of genetically modified (GM) foods and biopharmaceuticals. In this chapter, we describe how to use four popular allergenic prediction servers: (1) Structural Database of Allergenic Proteins (SDAP), (2) Allermatch, (3) Evaller 2, and (4) AlgPred. The first two prediction servers are(More)
Background: The pollen dispersal by wind is a natural event of great biological significance and an etiological factor in the genesis of allergic respiratory diseases. This is the first such study carried out in the city of Toluca, Mexico. Methods: The pollen was collected, using a Hirst type 7-day recording volumetric Spore Trap. According to the British(More)
Background: The pollen dispersal by wind is a natural event of great biological significance and an etiological factor in the genesis of allergic respiratory diseases. This is the first such study carried out in the city of Toluca, Mexico. Methods: The pollen was collected, using a Hirst type 7-day recording volumetric Spore Trap. According to the British(More)