Swati Garg

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Egress of malaria parasites from the host cell requires the concerted rupture of its enveloping membranes. Hence, we investigated the role of the plasmodial perforin-like protein PPLP2 in the egress of Plasmodium falciparum from erythrocytes. PPLP2 is expressed in blood stage schizonts and mature gametocytes. The protein localizes in vesicular structures,(More)
We propose an N-gram based approach to make predictions about the next event in a sequence of hospital admissions. To predict the value of a variable in the next admission (e.g. length of stay), we use only the sequence of values of the same variable for all hospital admissions of the same patient so far (e.g. the length of all previous hospital stays) and(More)
Malaria, a leading parasitic killer, is caused by Plasmodium spp. The pathology of the disease starts when Plasmodium merozoites infect erythrocytes to form rings, that matures through a large trophozoite form and develop into schizonts containing multiple merozoites. The number of intra-erythrocytic merozoites is a key-determining factor for multiplication(More)
The article by Ufuk F. et al. [1] on CT features of hepatic sarcoidosis was quite informative and made an interesting reading. Sarcoidosis is a systemic disorder of unknown etiology, characterized by non-caseating epitheloid granulomas. It has been suggested that sarcoidosis results from exposure to antigens like aerosols and infectious agents in(More)
BACKGROUND Spinal arteriovenous malformations (AVMs) can lead to development of congestive myelopathy (Foix-Alajouanine syndrome). Spinal AVMs are rare and so is this syndrome. Diagnosis is often missed due to its rarity and confusing definitions of the Foix-Alajouanine syndrome. CASE REPORT We report a case of a 47-year-old male patient suffering from(More)
Plasmodium falciparum perforin like proteins (PfPLPs) are an important arsenal for the entry and exit of malaria parasites. These proteins bind and oligomerize on the membrane in calcium dependent manner and form an open pore. The calcium dependent pore forming activity of PLPs is usually conferred by their C2 like C-terminal domain. Here, we have tried to(More)
UNLABELLED Wheat, the major source of vegetable protein in human diet, provides staple food globally for a large proportion of the human population. With higher protein content than other major cereals, wheat has great socio- economic importance. Nonetheless for wheat, three important fungal pathogens i.e. rust, smut and bunt are major cause of significant(More)
BACKGROUND Acute promyelocytic leukemia (APL) with t (15;17) is a distinct category of acute myeloid leukemia (AML) and is reported to show better response to anthracyclin based chemotherapy. A favorable overall prognosis over other subtypes of AML has been reported for APL patients but still about 15% patients relapse. METHODS This study evaluated the(More)