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In the present study, hepatoprotective and antioxidant properties of aqueous extract of Phyllanthus fraternus (AEPF 200, 300, and 400 mg/kg body weight (bw), orally) were investigated against cyclophosphamide (CPA 200 mg/kg, bw, intraperitoneally administered) induced liver damage in mice. Histopathological studies of CPA administration cause liver injury,(More)
Cyclophasphamide (CPA) is used to treat various types of cancer. It is a cytotoxic alkylating agent widely used in chemotherapeutic regimen. However, the clinical efficacy of CPA is marred by its side effects. In clinical applications of CPA, it becomes necessary to prevent the oxidative stress and reproductive toxicity induced thereby in normal cells. In(More)
*Correspondence: S. Lata. Department of Zoology, MMV, Banaras Hindu University, Varanasi, 221005, U.P, India. Tel.: +91 9415301826. Fax: +91 5422367927. E-mail: swarnlatabhu12@mail.com. K. N. Tiwari. Department of Botany, MMV, Banaras Hindu University, Varanasi, 221005, U.P, India. Tel.: +91 9335668374. Fax: +91 5422367927. E-mail: kntiwaribhu@gmail.com(More)
Concentrations of DDT, HCH, aldrin and endosulfan were determined in river dolphins from the River Ganges, Patna. Among the organochlorines studied in the dolphins, DDT concentration was highest followed by HCH. This shows exposure of dolphins to these organochlorine pesticides. Presences of organochlorines to higher degree in tissues suggest that the river(More)
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