Svetlana S. Missina

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The distribution of genotypes and alleles of ACE (I/D polymorphism), ACTN3 (R577X), NOS3 (5/4), UCP2 (Ala55Val), and UCP3 (-55C/T) genes, as well as the correlation between the genotype and physiological parameters, was studied in rowers (n = 230) and in a control group (n = 855). The genotypes were determined by analyzing restriction fragment length(More)
The subject of this study is the frequency distribution of alleles of the vascular endothelial growth factor gene (VEGF; the G-634C polymorphism) in athletes (n = 670) and in a control group (n = 1073) and the relationships of genotypes with aerobic performance in rowers (n = 90). Genetic typing was performed using the analysis of restriction fragment(More)
The goal of this study was to test the hypothesis that, in groups of highly trained endurance athletes (first and junior national teams), the final blood lactate concentration at maximum aerobic performance decreased as their training status increased. This study was performed with 20 physically active volunteers and 45 highly trained middle- and(More)
Physical load increases sympathetic nervous activity, which results in an increased cardiac output, constriction of peripheral vessels, and elevated systemic blood pressure. These changes are outcomes of two mechanisms: the central command from cerebral structures that trigger voluntary movements to activate the vasomotor center and the reflexes initiated(More)
The aim of study was to investigate an allelic distribution of PPARA (G/C polymorphism), PPARG (Pro/Ala), PPARD (+294T/C) and PGCIA (Gly482Ser) genes in rowers (n=205) and controls (n=659), and to find correlation between genotypes and physiological parameters. Genotyping was performed by restriction fragment length polymorphism analysis. Physiological(More)
The aim of the study was to investigate allelic distribution of calcineurin gene (CNB; 5I/5D polymorphism) in athletes of cyclic sports (n = 673) and controls (n = 1073), and to find interrelation between genotypes and risk of left ventricular hypertrophy and physical performance of athletes. Genotyping was performed by restriction fragment length(More)
Effects of 4-d dry immersion on metabolic-reflex regulation of hemodynamics were evaluated during local static work (30% of maximum voluntary effort) of the talocrural extensors. One group of immersed test-subjects received low-frequency electrostimulation of leg muscles to offset the immersion effect on EMG of working muscles. Metabolic-reflex regulation(More)
Vascular endothelial growth factor receptor 2 (VEGFR2) is essential to induce the full spectrum of VEGF angiogenic responses to aerobic training. In the present study, we examined the impact of the functional His472Gln polymorphism of the VEGFR2 gene on elite athlete status, endurance performance and muscle fibre type composition. Four hundred and(More)
The distribution of allele frequencies for the Ser12Thr mitochondrial transcription factor (TFAM) gene polymorphism was studied in athletes (n = 1537) and control subjects (n = 1113) and the relationship between genotypes and aerobic physical performance was estimated in boat racers (n = 90). Genotyping was performed using analysis of restriction fragment(More)
The aim of the study was to investigate allelic distribution of the mitochondrial transcription factor gene (TFAM) Ser12Thr polymorphism in athletes (n = 1537) and controls (n = 1113), and to find interrelation between genotypes and aerobic capacity in rowers (n = 90). Genotyping was performed by restriction fragment length polymorphism analysis. Aerobic(More)