Svetlana Miljkovic

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While the simian immunodeficiency virus (SIV)-infected rhesus monkey is an important animal model for human immunodeficiency virus type 1 (HIV-1) infection of humans, much remains to be learned about the evolution of the humoral immune response in this model. In HIV-1 infection, autologous neutralizing antibodies emerge 2 to 3 months after infection.(More)
Background Autologous neutralizing antibody responses against HIV1 have been shown to emerge a number of months after primary infection. It is not known why neutralizing antibodies against HIV-1 are relatively slow to appear. We use the SIV/rhesus macaque model to characterize the kinetics of autologous neutralizing antibody responses and envelope sequence(More)
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