Svetlana I Vojvodić

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INTRODUCTION Prions play a leading role in development of transmissible spongiform encephalopathies (TSE). These infectious particles, smaller than viruses and viroids, consist of special kind of proteins and don't contain nucleic acids. Due to that, they are named defective viruses. BIOCHEMICAL CHARACTERISTICS Prion protein determined as PrPcs was(More)
INTRODUCTION Despite engraftment and function of graft after hematopoietic stem cell transplantation severe immune suppression is a characteristics of early posttransplant period. Primary parameters contributing to posttransplant immuno-incompetence include: lack of sustained transfer of donor antigen specific immunity, recapitulation of immunological(More)
INTRODUCTION One of the most fascinating areas of research within the field of histocompatibility at present time concerns an observation that a major human histocompatibility system, HLA, is deeply involved in development of a great number of diseases. MATERIALS AND METHODS HLA class I antigens were investigated in 225 cases with various kinds of(More)
UNLABELLED INTRODUCTION; Natural Killer cells (NK cells) represent the subset of peripheral lymphocytes that play critical role in the innate immune response to virus-infected and tumor transformed cells. Lysis of NK sensitive target cells could be mediated independently of antigen stimulation and without requirement of peptide presentation by the major(More)
INTRODUCTION The distribution of HLA genes and haplotypes in the normal population is of considerable importance in disease susceptability studies, population and genetic studies and tissue and organ transplantation. The HLA phenotype frequencies can be used for the estimation of the probability of finding phenotypically identical unrelated volunteer bone(More)
INTRODUCTION Investigations of factors responsible for the disturbance of fetomaternal tolerance during pathological pregnancies and causes of recurrent spontaneous abortions are pointing that HLA antigens play a key role in their development. Rejection of semiallogeneic allograft in this pregnancy disorder is a consequence of interaction between genetic(More)
There are numerous studies showing the role of human leukocyte antigens (HLAs) related with susceptibility or resistance to certain diseases. The aim of this study was to determine the association of HLA-B27 with ankylosing spondylitis (AS), polyarthralgia, lumboishialgia, acute anterior uveitis (AAU), psoriatic arthritis (PA), synovitis coxae and(More)
INTRODUCTION Since the discovery of major histocompatibility complex influence on cause leukaemia in 1964, an HIA association with leukaemia in humans has been considered as a possible genetic risk factor that contributes to development of leukaemia. In addition to associations of several HLA antigens with leukaemias, it has been observed that patients with(More)
INTRODUCTION M and N blood group antigens demonstrate inhibitory activity in inhibition reaction of viral hemagglutination with some influenza virus strains, with help of N-acetylneuraminic acid (sialic acid) which occurs in glycophorins on the red blood cells surface, and represent specific hemagglutunation receptors and substrate for action of influenza(More)