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- Sverker Nystedt, Karin Emilsson, Claes Wahlestedt, J. Sundelin
- Proceedings of the National Academy of Sciences…
- 1994
A DNA sequence encoding a G-protein-coupled receptor was isolated from a mouse genomic library. The predicted protein is similar in structure to the thrombin receptor and has a similar activation… (More)
- Brian D. Blackhart, Karin Emilsson, +5 authors Robert Murry Scarborough
- The Journal of biological chemistry
- 1996
Recently, a second member of the protease-activated receptor (PAR) family, named PAR-2, has been identified. Similar to the thrombin receptor, PAR-2 appears to be activated by proteolytic-mediated… (More)
- Carsten Horn, Nils Offen, Sverker Nystedt, Udo Häcker, Ernst A Wimmer
- Genetics
- 2003
Transposon mutagenesis provides a fundamental tool for functional genomics. Here we present a non-species-specific, combined enhancer detection and binary expression system based on the transposable… (More)
- Yoshikazu Nakano, Sverker Nystedt, Anish A. Shivdasani, Helen L. Strutt, Christoph Thomas, Philip W Ingham
- Mechanisms of Development
- 2004
The Hedgehog signalling pathway is deployed repeatedly during normal animal development and its inappropriate activity is associated with various tumours in human. The serpentine protein Smoothened… (More)
- Sverker Nystedt, Karin Emilsson, Anna Karin Larsson, Bodil Strömbeck, J. Sundelin
- European journal of biochemistry
- 1995
We previously reported the molecular cloning of a mouse guanosine-nucleotide-binding-protein-coupled receptor similar to the thrombin receptor. Since the physiological agonist was unknown, the… (More)
- Philip W Ingham, Sverker Nystedt, +4 authors Andrew M Taylor
- Current Biology
- 2000
Hedgehog (Hh) signalling plays a central role in many developmental processes in both vertebrates and invertebrates [1]. The multipass membrane-spanning proteins Patched (Ptc) [2-4] and Smoothened… (More)
The proteinase-activated receptor 2 (PAR-2) belongs to the family of seven transmembrane region receptors, and, like the related thrombin receptor, it is activated by specific proteolytic cleavage of… (More)
- Sverker Nystedt, Vanitha Ramakrishnan, Johan Sundelin
- The Journal of biological chemistry
- 1996
The proteinase-activated receptor 2 (PAR-2) belongs to the family of seven transmembrane region receptors, and, like the related thrombin receptor, it is activated by specific proteolytic cleavage of… (More)
- Udo Hacker, Sverker Nystedt, Mojgan Padash Barmchi, Carsten Horn, Ernst A Wimmer
- Proceedings of the National Academy of Sciences…
- 2003
P element-mediated mutagenesis has been used to disrupt an estimated 25% of genes essential for Drosophila adult viability. Mutation of all genes in the fly genome, however, poses a problem, because… (More)
- Karin Emilsson, Claes Wahlestedt, M K Sun, Sverker Nystedt, C H Owman, J. Sundelin
- Journal of vascular research
- 1997
Proteinase-activated receptor 2 (PAR-2) is a G protein-coupled receptor related to the thrombin receptor. PAR-2 can be activated by trypsin and by synthetic peptides corresponding to the new amino… (More)