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Comparison of strand-specific transcriptomes of enterohemorrhagic Escherichia coli O157:H7 EDL933 (EHEC) under eleven different environmental conditions including radish sprouts and cattle feces
BackgroundMultiple infection sources for enterohemorrhagic Escherichia coli O157:H7 (EHEC) are known, including animal products, fruit and vegetables. The ecology of this pathogen outside its humanExpand
Bridging the Gap of Domain and Visualization Experts with a Liaison
We introduce the role Liaison for design study projects. With considerable expertise in visualization and the application domain, a Liaison can help to foster richer and more effectiveExpand
Visual Boosting in Pixel‐based Visualizations
In this paper we compare different approaches for visual boosting in pixel‐based visualizations with respect to their effectiveness in boosting single pixels, trends, and interesting passages. Expand
Mining Rare Associations between Biological Ontologies
The constantly increasing volume and complexity of available biological data requires new methods for their management and analysis. An important challenge is the integration of information fromExpand
Probiotic Enterococcus faecalis Symbioflor® down regulates virulence genes of EHEC in vitro and decrease pathogenicity in a Caenorhabditis elegans model
Enterohemorrhagic E. coli O157:H7 (EHEC) shorten the lifespan of Caenorhabditis elegans compared to avirulent bacteria. Co-feeding EHEC with Enterococcus faecalis Symbioflor® significantly increasedExpand
Proteomic Profiling of Serological Responses to Aspergillus fumigatus Antigens in Patients with Invasive Aspergillosis.
Aspergillus fumigatus is the species that most commonly causes the opportunistic infection invasive aspergillosis (IA) in patients being treated for hematological malignancies. Little is known aboutExpand
Visual Analytics for the Prediction of Movie Rating and Box Office Performance
This paper describes our solution to the IEEE VAST 2013 Mini Challenge 11. Expand
Differentiation of ncRNAs from small mRNAs in Escherichia coli O157:H7 EDL933 (EHEC) by combined RNAseq and RIBOseq – ryhB encodes the regulatory RNA RyhB and a peptide, RyhP
BackgroundWhile NGS allows rapid global detection of transcripts, it remains difficult to distinguish ncRNAs from short mRNAs. To detect potentially translated RNAs, we developed an improved protocolExpand
Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC)
BackgroundGenomes of E. coli, including that of the human pathogen Escherichia coli O157:H7 (EHEC) EDL933, still harbor undetected protein-coding genes which, apparently, have escaped annotation dueExpand
Evidence for the recent origin of a bacterial protein-coding, overlapping orphan gene by evolutionary overprinting
BackgroundGene duplication is believed to be the classical way to form novel genes, but overprinting may be an important alternative. Overprinting allows entirely novel proteins to evolve de novo,Expand