Sven Van den Bosch

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In recent years, large discrepancies were described in the success rate of the tyrosinase reverse transcription polymerase chain reaction (RT-PCR) for detecting melanoma cells in the peripheral blood of melanoma patients. We present a quality control study in which we analysed the reproducibility of detection of tyrosinase and MART-1 transcripts in 106(More)
 An increased rate of obstruction of peritoneal dialysis catheters is observed during peritonitis. Hypercoagulation and hypofibrinolysis may explain this increased occurrence. We studied plasminogen activator inhibitor type 1 antigen (PAI-1), tissue-type plasminogen activator antigen (t-PA), D-dimer (DD), plasmin-α2-antiplasmin complexes (PAP), and(More)
IP Differentiated Services is widely seen as the framework to provide Quality of Service (QoS) in the Internet in a scalable fashion. However many issues have still not been fully addressed, such as: the way Per-Hop Behaviours can be combined to provide end-to-end services; the specification of admission control and resource reservation mechanisms; and the(More)
In this paper, an off-line traffic engineering algorithm is presented that optimizes the single-path routing of Label Switched Paths in a Differentiated Services IP domain by means of explicit, Multi-Protocol Label Switching controlled nonshortest paths. This algorithm allows traffic engineering up to 2500 traffic trunks in flat networks with sizes up to(More)
PNU-159548 (4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin) is the lead compound of a novel class of cytotoxic agents (alkycyclines) with a unique mechanism of action combining DNA intercalation with alkylation of guanines in the DNA major groove. The objectives of two phase I studies were to assess the dose-limiting toxicities (DLTs),(More)
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