• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • Sebastian Altenhöfer, Ines Witte, +8 authors Sven Horke
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2010 (First Publication: 6 August 2010)
  • The human enzyme paraoxonase-2 (PON2) has two functions, an enzymatic lactonase activity and the reduction of intracellular oxidative stress. As a lactonase, it dominantly hydrolyzes bacterialContinue Reading
  • Sven Horke, Ines Witte, Petra Wilgenbus, Maximilian Krüger, Dennis Strand, Ulrich Förstermann
  • Biology, Medicine
  • Circulation
  • 2007 (First Publication: 17 April 2007)
  • BACKGROUND In the vascular system, elevated levels of reactive oxygen species (ROS) produce oxidative stress and predispose to the development of atherosclerosis. Therefore, it is important toContinue Reading
  • John F. Teiber, Sven Horke, +5 authors Dragomir I Draganov
  • Biology, Medicine
  • Infection and immunity
  • 2008 (First Publication: 1 June 2008)
  • The pathogenic bacterium Pseudomonas aeruginosa causes serious infections in immunocompromised patients. N-(3-oxododecanoyl)-L-homoserine lactone (3OC12-HSL) is a key component of P. aeruginosa'sContinue Reading
  • Sven Horke, Ines Witte, +9 authors John F. Teiber
  • Medicine, Biology
  • The Biochemical journal
  • 2010 (First Publication: 15 February 2010)
  • Two virulence factors produced by Pseudomonas aeruginosa are pyocyanin and N-(3-oxododecanoyl)-L-homoserine lactone (3OC12). Pyocyanin damages host cells by generating ROS (reactive oxygen species).Continue Reading
  • Katja Steinkamp-Fenske, Larissa Bollinger, +4 authors Huige Li
  • Medicine, Chemistry
  • The Journal of pharmacology and experimental…
  • 2007 (First Publication: 1 August 2007)
  • Nitric oxide (NO) produced by endothelial NO synthase (eNOS) is a protective principle in the vasculature. Many cardiovascular diseases are associated with reduced NO bioactivity and eNOS uncouplingContinue Reading