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PURPOSE The objective of this study was to determine the impact of family income and sickle cell disease on the health-related quality of life (HRQL) of children. METHODS This was a cross-sectional study of children with and without sickle cell disease. Participants completed the PedsQL generic core scales parent-proxy or child self-report questionnaire(More)
BACKGROUND The opioid meperidine induces spinal anesthesia and blocks nerve action potentials, suggesting it is a local anesthetic. However, whether it produces effective clinical local anesthesia in peripheral nerves remains unclear. Classification as a local anesthetic requires clinical local anesthesia but also blockade of voltage-dependent Na+ channels(More)
OBJECTIVES To determine 1) the frequency of missed vaccine opportunities (VOs) in inner city children </=3 years of age; 2) whether the recommended vaccine(s) were given within 6 months of the missed opportunity (MO); 3) whether these vaccinations were age-appropriate according to the guidelines of the Advisory Committee on Immunization Practices; and 4)(More)
Vaccines are one of the greatest public health achievements, preventing both mortality and morbidity. However, overall immunization rates are still below the 90% target for Healthy People 2020. There remain significant disparities in immunization rates between children of different racial/ethnic groups, as well as among economically disadvantaged(More)
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