Suzzane A Maher

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In vitro pre-clinical tests of hip prostheses have not yet been developed to the extent that inferior prostheses can be 'screened-out' prior to animal or clinical trials. This paper reports the experimental part of a project to develop a pre-clinical testing platform for cemented femoral hip implants. It is based on the clinical observation (Kärrholm et al.(More)
The lack of integration between implants and articular cartilage is an unsolved problem that negatively impacts the development of treatments for focal cartilage defects. Many approaches attempt to increase the number of matrix-producing cells that can migrate to the interface, which may help to reinforce the boundary over time but does not address the(More)
Preclinical testing of orthopaedic implants is becoming increasingly important to eliminate inferior designs before animal experiments or clinical trials are begun. Preclinical tests can include both laboratory bench tests and computational modeling. One problem with bench tests is that variability in prosthesis insertion can significantly influence the(More)
OBJECTIVE To develop a method to measure the migration of a cemented hip prosthesis in an in vitro experimental test. DESIGN A device to measure prosthesis movement relative to bone was designed and fabricated. It was tested using a Lubinus prosthesis (W. Link, Germany) implanted in a composite femur. BACKGROUND Clinical studies using(More)
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