Suzanne L. Porter

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Production of recombinant subunit vaccines in transgenic plants may be a means of reducing vaccine costs while increasing availability and safety. A plant-derived product found safe and effective for oral administration would provide additional advantages when used as a vaccine. Outstanding issues with the technology include transgene stability through(More)
Rice flour is a well-known and characterized source of pharmaceutical ingredients, which are gluten-free and incorporated in many drug delivery applications such as excipient starch. To further exploit this uniqueness, the synthetic capacity of rice endosperm tissue, the basis of rice flour, was extended by genetic transformation. Recombinant human GM-CSF,(More)
The use of transgenic plants in the production of recombinant proteins for human therapy, including subunit vaccines, is being investigated to evaluate the efficacy and safety of these emerging biopharmaceutical products. We have previously shown that synthesis of recombinant glycoprotein B (gB) of human cytomegalovirus can be targeted to seeds of(More)
A plant based high fidelity vaccine production system is being developed with emphasis on producing antigens capable of being orally delivered in multivalent or subunit plant packets. Plant-based edible vaccines may provide an attractive, safe and inexpensive alternative to conventional vaccine production. Edible plant tissues are not normally antigenic in(More)
s from all researchers who are engaged with the seriously ill, frail elderly. Authors: John Muscedere1 MD, Sarah Grace Bebenek2 MSc, Denise Stockley PhD2, Laura Kinderman2 PhD, and Carol Barrie1 CPA, CA. 1Canadian Frailty Network, 2Queen’s University. Ultrasound of Thigh Muscle Can Predict Frailty in Elderly Patients S. Salim, L. Warkentin, A. Gallivan, T.(More)
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