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Autosomal recessive primary microcephaly is a potential model in which to research genes involved in human brain growth. We show that two forms of the disorder result from homozygous mutations in the genes CDK5RAP2 and CENPJ. We found neuroepithelial expression of the genes during prenatal neurogenesis and protein localization to the spindle poles of(More)
OBJECTIVE To investigate the influence of educational activity in the school environment based on prescriptive and subjective oral health indicators. METHODS Cross-sectional, comparative study involving students between 9 and 12 years of age, from schools that have educational activities and those that do not, designated schools A and B. The oral health(More)
Frequency of new copy number variation in humans pp333-334 Gert-Jan B van Ommen Book Review The unwanted p335 Reviewed by: Elof Axel Carlson News and Views Partners in crime pp337-338 Touching base p346 Research Highlights p347 Brief Communications Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons pp349-350
OBJECTIVE To test whether customised (ct) growth criteria are more reliable than standard (st) ones to predict intrauterine insult. PATIENTS 32 mothers and their singleton term neonates selected as small for gestational age (st-SGA=8) or appropriate for gestational age (st-AGA=24). MAIN OUTCOME MEASURES Nitric oxide, high-sensitive C reactive protein(More)
We provide and discuss a floristic survey of herbaceous and subshrubby aquatic and palustrine angiosperms of Viruá National Park (VNP). The VNP is located in the northern Amazon basin and displays phytophysiognomies distributed in a mosaic where these plants occur, as flooded forests, hydromorphic white-sand savannas, "buritizais" and waterbodies. After(More)
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