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OBJECTIVE The purpose of our study was to explore the feasibility and utility of 2D chemical shift imaging (CSI) MR spectroscopy in the evaluation of new areas of contrast enhancement at the site of a previously treated brain neoplasm. MATERIALS AND METHODS Two-dimensional CSI (point-resolved spectroscopy sequence [PRESS]; TR/TE, 1,500/144) was performed(More)
BACKGROUND With knee morphology being a non-modifiable anterior cruciate ligament injury risk factor, its consideration within injury prevention models is limited. Knee anatomy, however, directly influences joint mechanics and the potential for injurious loads. With this in mind, we explored associations between key knee anatomical and three-dimensional(More)
P-selectin inhibition has been shown to decrease thrombogenesis in multiple animal species. In this study, we show that a novel oral small-molecule inhibitor of P-selectin, PSI-697, promotes thrombus resolution and decreases inflammation in a baboon model of venous thrombosis. Experimental groups consisted of the following: 1) primates receiving a single(More)
This study seeks to quantify differences in anterior vaginal wall prolapse during sequential Valsalva attempts on dynamic magnetic resonance imaging (MRI). Subjects were taken from an on-going case–control study evaluating anterior vaginal wall prolapse. Women with a prolapse whose leading edge extended ≥1 cm beyond the hymenal ring were included (n = 40).(More)
RATIONALE AND OBJECTIVES Metabolite peak boundary definition is an important postprocessing step in proton magnetic resonance spectroscopy (1H-MRS). We compare metabolite ratios calculated using three different postprocessing strategies: software-rendered default peak boundaries, manually adjusted peak boundaries and a curve-fitting program. The first two(More)
BACKGROUND AND PURPOSE The lateral tentorial sinus (LTS) has not been well described in the imaging literature. The aim of this study was to investigate the value of MR imaging in assessing the LTS, which may provide guidance for preoperative planning. METHODS Fifty-five adult patients underwent MR imaging of the brain. Four neuroradiologists evaluated(More)
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