Suyan Li

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Current models of brain development support the view that VEGF, a signaling protein secreted by neuronal cells, regulates angiogenesis and neuronal development. Here we demonstrate an autonomous and pivotal role for endothelial cell-derived VEGF that has far-reaching consequences for mouse brain development. Selective deletion of Vegf from endothelial cells(More)
Neuronal migration, a key event during brain development, remains largely unexplored in the mesencephalon, where dopaminergic (DA) and GABA neurons constitute two major neuronal populations. Here we study the migrational trajectories of DA and GABA neurons and show that they occupy ventral mesencephalic territory in a temporally and spatially specific(More)
BACKGROUND CENP-E, one of spindle checkpoint proteins, plays a crucial role in the function of spindle checkpoint. Once CENP-E expression was interrupted, the chromosomes can not separate procedurally, and may result in aneuploidy which is a hallmark of most solid cancers, such as hepatocellular carcinoma (HCC). We investigate the expression of CENP-E in(More)
State-owned forestry enterprises are important elements of the forestry economy in China. The operational efficiency of such enterprises depends on technological progress and other input factors. Total factor productivity (TFP) is an important means to evaluate the efficiency of technical elements. The growth of production efficiency can be classified into(More)
Forest and soil types are the main factors that influence the distribution pattern of soil organic carbon (SOC) in forests across east China. In general, SOC density was largest in north-eastern China, followed by south-eastern China, and lowest in middle-eastern China, due to regional climate and the dominant forest type (young plantations in(More)
A laboratory microcosm experiment was conducted to determine whether the earthworm Eisenia fetida could survive in a saline soil from a field site in North China, and an experiment using response surface methodology was conducted at that field site to quantify the effects of E. fetida and green waste compost (GWC) on the salt content of the soil. The(More)
  • Stefan G. Tullius, Hector Rodriguez Cetina Biefer, Suyan Li, Alexander J. Trachtenberg, Karoline Edtinger, Markus Quante +15 others
  • 2014
CD4(+) T cells are involved in the development of autoimmunity, including multiple sclerosis (MS). Here we show that nicotinamide adenine dinucleotide (NAD(+)) blocks experimental autoimmune encephalomyelitis (EAE), a mouse model of MS, by inducing immune homeostasis through CD4(+)IFNγ(+)IL-10(+) T cells and reverses disease progression by restoring tissue(More)
Midbrain GABA neurons, endowed with multiple morphological, physiological and molecular characteristics as well as projection patterns are key players interacting with diverse regions of the brain and capable of modulating several aspects of behavior. The diversity of these GABA neuronal populations based on their location and function in the dorsal, medial(More)