Susumu Takeuchi

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BACKGROUND Anisotropic conduction properties may provide a substrate for reentrant arrhythmias. We investigated the age-dependent changes of structural and functional anisotropy in isolated right atria from infant (1 to 2 months), young (6 to 12 months), and old (6 to 10 years) dogs. METHODS AND RESULTS The histology of the mapped atrial tissues (a small(More)
In vitro dissolution tests are performed for new formulations to evaluate in vivo performance, which is affected by the change of gastrointestinal (GI) physiology, in the GI tract. Thus, those environmental changes should be introduced to an in vitro dissolution test. Many studies have successfully shown the improvement of in vitro-in vivo correlations(More)
In the ubiquitous computing environment, we believe that P2P-based context-aware application utilizing sensing data is important. However, since sensors are not placed under the control of one specific entity, it is difficult to retrieve appropriate information from the distributed sensors. In addition, when the same queries are sent by different users,(More)
This paper describes a method to achieve a visioncued swaying task in unknown environments utilizing adaptive visual servoing. The proposed method has a hybrid structure consisting of a controller to keep the distances between feet constant (a stance servoing controller), and an adaptive visual servoing controller. Making use of the method, the motion of(More)
BACKGROUND Atrial fibrillation (AF) is an arrhythmia associated with functional and morphological remodeling of atria. We investigated the distribution and the expression of connexins in atrial tissues from patients with chronic AF and left atrial dilatation (AD). METHODS AND RESULTS Immunohistochemistry was performed in atrial tissues obtained during(More)
In this study, the data of 113 human bioequivalence (BE) studies of immediate release (IR) formulations of 74 active pharmaceutical ingredients (APIs) conducted at Sawai Pharmaceutical Co., Ltd., was analyzed to understand the factors affecting intra- and intersubject variabilities in oral drug absorption. The ANOVA CV (%) calculated from area under the(More)
Geographical contour lines are often used for the analysis of the sensor data distribution on wide area. In this paper, we propose a method to reconstruct contour lines by collecting sensor data from widely distributed sensors. In this case, it is redundant to collect all sensors from wide area since geographically closed sensors sense similar data. We(More)
In this paper, we propose an overlay network called HDOV, a hierarchical extension of Delaunay overlay network for data collection with multiple spatial resolutions. By using HDOV, spatial data with at least specified spatial resolution can be collected reducing the redundant messages for data collection from wide area peer-to-peer network. The proposal in(More)