Susumu Nishino

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Partial phenylcarbamoylation of ribonucleosides by metal carboxylates - phenyl isocyanate system was found to be induced at 2'-position with high regioselectivity in good yields, similar to that by amines - phenyl isocyanate system; these results prompted us to perform synthesis of oligoribonucleotides bearing 2'-5' phosphodiester linkage starting either(More)
BACKGROUND Currently, high-density lipoprotein cholesterol (HDL-C), a factor which prevents progression of arteriosclerosis, is measured using laboratory-based chemistry analyzers without a pretreatment step. Because HDL-C is measured with a pretreatment step in many point-of-care testing systems, a direct assay is needed. METHODS A dry-chemistry-based(More)
The title linker was synthesized in the manner of dimer-units introduction through liquid-phase and phosphoroamidate approaches involving deamidation with tetrabutylammonium nitrite-acetic anhydride.
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