Susie ElSaadany

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Creutzfeldt-Jakob disease (CJD) has been considered infectious since the mid-1960s, but its transmissibility through the transfusion of blood or blood products is controversial. The causative agent's novel undefined nature and resistance to standard decontamination, the absence of a screening test, and the recognition that even rare cases of transmission(More)
INTRODUCTION A descriptive epidemiological analysis to update trends of Creutzfeldt-Jakob disease (CJD) deaths, from 1979-2001, was undertaken. METHODS Cases with CJD as underlying cause were extracted. Age-adjusted death rates by age, sex, and province were calculated. Information on birthplace, autopsy indications and type of work were examined for(More)
A descriptive analysis of hepatocellular carcinoma (HCC) deaths in Canada for 1995 was undertaken. Cases (ICD-9 155.0) were identified from the Statistics Canada annual mortality file; age-adjusted death rates by age, sex and province were calculated. Antecedent causes and conditions leading to death listed on the death certificate, including viral(More)
BACKGROUND AND METHODS To provide information on poorly described Canadian hepatocellular cancer epidemiology, we analyzed incident cases abstracted from the Canadian Cancer Registration Database (1969-1997) and Canadian annual death data (1969-1998). Age, sex, geographic distribution, and secular trends were described. Projection models were developed for(More)
BACKGROUND When comparing transfused versus nontransfused patients, erythrocyte transfusion is consistently associated with increased mortality. Nonetheless, unmeasured confounding may unduly influence this comparison. This unmeasured risk may have less influence on comparisons of patients undergoing surgery at hospitals with differing transfusion rates. (More)
Using expert judgment data from the TU Delft's expert judgment data base, we compare the performance of different weighting schemes, namely equal weighting, performance based weighting from the classical model (Cooke, 1991), social network weighting and likelihood weighting. The picture that emerges with regard to social network weights is rather mixed. SN(More)
There is a high level of uncertainty surrounding the potential for iatrogenic prion transmission through transplantation, medical instrument reuse, blood transfusion, and blood product use due to a lack of evidence-based research on this important risk issue. A group of specialists was enlisted to evaluate some of the knowledge gaps in this area using the(More)
BACKGROUND Current practice in transfusion medicine promotes clear documentation of transfusion-related events including the fact that the patient has been informed of the related risks and benefits. STUDY DESIGN AND METHODS A retrospective review of 1005 patient charts was carried out to determine documentation. RESULTS Most patients were from general(More)
Autologous blood donation (ABD) has been widely recommended. Data from one of the oldest hospital-based programmes in Canada describe both activities and drawbacks. Data were compared over the nearly two decades of activity that peaked in 1996. A 5-year review of recent activity showed that of the 2410 patients referred for consideration, 1823 (75.64%) were(More)
OBJECTIVES To estimate the incidence of and to describe the risk factors that were associated with the acquisition of hepatitis A, B, and C in well-defined Canadian populations from the Sentinel Health Unit Surveillance System (SHUSS). METHODS We used the 1993 to 1995 data on hepatitis A, B, and C infection in Canada, collected by SHUSS, a national(More)