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Structure-activity relationship of the pro- and anticoagulant effects of Fucus vesiculosus fucoidan.
- Z. Zhang, S. Till, +5 authors M. Dockal
- Chemistry, Medicine
- Thrombosis and haemostasis
- 28 November 2013
Fucoidan is a highly complex sulfated polysaccharide commonly extracted from brown seaweed. In addition to their many biological activities, fucoidans have recently been demonstrated to inhibit or… Expand
Screening of complex fucoidans from four brown algae species as procoagulant agents.
Fucoidans are complex sulfated polysaccharides extracted from brown algae. Depending on the concentration, they have been shown to stimulate and inhibit blood coagulation in vitro. Promotion of… Expand
Anticoagulant Activity and Mechanism of Non-Anticoagulant Sulfated Polysaccharides
Abstract 1208 Fucoidans are sulfated polysaccharides which are extracted from brown seaweeds and echinoderms and have a wide variety of biological activities. Described as non-anticoagulant… Expand
Structure-Activity Relationship of Pro- and Anticoagulant Effects of Fucus Vesiculosus Fucoidan
Abstract 3353 Fucoidans are sulfated polysaccharides extracted from brown algae. Fucoidans have a wide variety of biological activities including pro- and anticoagulant activities, which occur at… Expand
The Application of Thrombin Generation Test Is Compromised By Antithrombin III Deficiency
Background: Antithrombin III (ATIII) is a stoichiometric inhibitor of factor Xa and thrombin and a major physiological regulator of coagulation. Reduction of ATIII levels, for example in patients… Expand
Structural and Functional Characterization of Fucoidan and Its Procoagulant Effect in An Ex Vivo Model of Factor VIII-Inhibited Guinea Pigs
Abstract 2262 Fucoidans are sulfated polysaccharides extracted and purified from brown seaweeds. Described as non-anticoagulant polysaccharides (NASPs), they have been shown to improve clotting in… Expand