Susanne Rotter

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We are especially thankful to Christina Meskers, Umicore, for her valuable contributions to the manuscript. We are grateful for comments on earlier drafts of this report by J. Guido Sonnemann, UNEP, supervised the preparation of this report and provided valuable input and comments. Thanks go to Ernst Ulrich von Weizsäcker and Ashok Khosla as co-chairs of(More)
Silymarin is a hepatoprotective mixture of flavonolignans and flavonoids extracted from the seeds of milk thistle (Silybum marianum L. Gaertn). This study investigates the effect of major bioactive constituents from silymarin, silybin A, silybin B, isosilybin A, isosilybin B, silydianin, silychristin, isosilychristin, and taxifolin, on the expression of(More)
SCOPE Increased macrophage cholesterol efflux (ChE) is considered to have anti-atherosclerotic effect counteracting cardiovascular disease. The principle pungent ingredient of the fruits of Piper nigrum, piperine, is identified in this study as a ChE inducer in THP-1-derived macrophages, and mechanisms underlying this effect are explored. METHODS AND(More)
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