Susanne Rautiainen

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BACKGROUND Experimental animal studies have shown adverse effects of high-dose vitamin C supplements on age-related cataract. OBJECTIVE We examined whether vitamin C supplements (approximately 1000 mg) and multivitamins containing vitamin C (approximately 60 mg) are associated with the incidence of age-related cataract extraction in a population-based,(More)
BACKGROUND AND PURPOSE Consumption of antioxidant-rich foods may reduce the risk of stroke by inhibition of oxidative stress and inflammation. Total antioxidant capacity (TAC) takes into account all antioxidants and the synergistic effects between them. We examined the association between dietary TAC and stroke incidence in cardiovascular disease (CVD)-free(More)
BACKGROUND Dietary supplements are widely used in industrialized countries. OBJECTIVE The objective was to examine the association between multivitamin use and myocardial infarction (MI) in a prospective, population-based cohort of women. DESIGN The study included 31,671 women with no history of cardiovascular disease (CVD) and 2262 women with a history(More)
BACKGROUND There are no previous studies investigating the effect of all dietary antioxidants in relation to myocardial infarction. The total antioxidant capacity of diet takes into account all antioxidants and synergistic effects between them. The aim of this study was to examine how total antioxidant capacity of diet and antioxidant-containing foods were(More)
OBJECTIVES the results of experimental studies suggest that vitamin D deficiency activates the renin-angiotensin system and predisposes to hypertension. Results of previous epidemiological studies investigating the association between 25-hydroxyvitamin D [25(OH)D] status and hypertension have not been consistent, perhaps because of their sole reliance on(More)
BACKGROUND Total antioxidant capacity (TAC) provides an assessment of antioxidant activity and synergistic interactions of redox molecules in foods and plasma. OBJECTIVE We investigated the validity and reproducibility of food-frequency questionnaire (FFQ)-based TAC estimates assessed by oxygen radical absorbance capacity (ORAC), total radical-trapping(More)
IMPORTANCE To our knowledge, no previous epidemiologic study has investigated the association between all antioxidants in the diet and age-related cataract. The total antioxidant capacity (TAC) concept aims to measure the capacity from all antioxidants in the diet by also taking synergistic effects into account. OBJECTIVE To investigate the association(More)
We examined the associations of high-dose supplements of vitamins C and E and low-dose multivitamins with the risk of age-related cataract among 31,120 Swedish men, aged 45-79 years, in a population-based prospective cohort. Dietary supplement use was assessed from a questionnaire at baseline in 1998. During follow-up (January 1998-December 2006), 2,963(More)
BACKGROUND Studies have reported inconsistent findings on the association between dairy product intake and weight change and obesity. Only a few prospective studies have investigated the role of dairy consumption in both weight change and risk of becoming overweight or obese and whether these associations depend on the initial body weight. OBJECTIVE We(More)
BACKGROUND Fruit, vegetable, and dietary fiber intake have been associated with lower risk of cardiovascular disease (CVD); however, little is known about their role in obesity prevention. OBJECTIVE Our goal was to investigate whether intake of fruits, vegetables, and dietary fiber is associated with weight change and the risk of becoming overweight and(More)