Susanne Gantner

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The glucose transporter isoform 1 (GLUT1; SLC2A1) is a key rate-limiting factor in the transport of glucose into cancer cells. Enhanced GLUT1 expression and accelerated glycolysis have been found to promote aggressive growth in a range of tumor entities. However, it was unknown whether GLUT1 directly impacts metastasis. Here, we aimed at analyzing the(More)
Malignant melanoma (MM) represents the most severe skin cancer (1). Somatic ErbB4 gene mutations have been identified in 19% of individuals with MM (2). These mutations result in hyperactivation of the ErbB4 receptor (2, 3). This finding indicates a pivotal role of the ErbB4 receptor tyrosine kinase (RTK) in the tumourigenesis of MM. However, oncogenic(More)
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