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OBJECTIVE To describe the development and pilot testing of a set of admissions instruments based on the McMaster University multiple mini-interview (MMI) and designed to assess desirable, non-cognitive characteristics in order to inform final decisions on candidate selection for entry to medical school. METHODS Community and faculty consultation on(More)
Because staphylococcal protein A binds all the known subclasses of mouse IgG except IgG1, ethanol-fixed staphylococci were used as an adsorbent to prepare IgG1 fractions of anti-BALB/c alloantibody-containing globulins and normal globulins of the same strains. The loss of more than 99% of the IgG2 as a result of this adsorption was demonstrated by(More)
Lymph node cells of rabbits injected with sheep erythrocytes, identified as antibody-producing by their ability to produce plaques of hemolysis in erythrocyte-containing agar layers, have been examined by electron microscopy, by the use of a procedure devised for subjecting single cells to such examination. The antibody-producing cells thus examined were(More)
It was demonstrated by Keogh et al. (1947) and Warburton et al. (1949) that several products of bacterial cultures could be adsorbed to erythrocytes, which then could be agglutinated by sera containing antibodies to those bacterial antigens. This approach was developed in the case of a constituent of tuberculin by Middlebrook and Dubos (1948) and Rothbard(More)
At various intervals, from 10 minutes to 21 days, after the injection of dysentery bacilli into the hind foot pads of rabbits the popliteal lymph nodes were excised. The cells of the lymph nodes were teased free, washed, and injected intravenously into normal rabbits. In each case aliquots of the same cell suspension were either incubated at 37 degrees C.(More)