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  • David M. Valenzuela, Trevor N. Stitt, Peter S. DiStefano, Eduardo Rojas, Karen Mattsson, Debra L. Compton +12 others
  • 1995
While a number of growth factors have been described that are highly specific for particular cell lineages, neither a factor nor a receptor uniquely specific to the skeletal muscle lineage has previously been described. Here we identify a receptor tyrosine kinase (RTK) specific to skeletal muscle, which we term "MuSK" for muscle-specific kinase. MuSK is(More)
  • Thomas M DeChiara, David C Bowen, David M Valenzuela, Mary V Simmons, William T Poueymirou, Susan Thomas +9 others
  • 1996
Formation of neuromuscular synapses requires a series of inductive interactions between growing motor axons and differentiating muscle cells, culminating in the precise juxtaposition of a highly specialized nerve terminal with a complex molecular structure on the postsynaptic muscle surface. The receptors and signaling pathways mediating these inductive(More)
  • James J Hartman, Jeff Mahr, Karen McNally, Katsuya Okawa, Akihiro Iwamatsu, Susan Thomas +4 others
  • 1998
Microtubule disassembly at centrosomes is involved in mitotic spindle function. The microtubule-severing protein katanin, a heterodimer of 60 and 80 kDa subunits, was previously purified and shown to localize to centrosomes in vivo. Here we report the sequences and activities of the katanin subunits. p60 is a new member of the AAA family of ATPases, and we(More)
  • Percy W Abrams, Matthew Dryer, Wolfgang Woïck, Aksodahah Phoebe Hill, Eva Okun, Nora Carrier +54 others
  • 2006
But, especially to Karin Michelson for all of the help. I would like to acknowledge the encouragement and help given to me by the following people and organizations: First and foremost, the Onondaga speakers: There are so many people to thank that I hope I haven't forgotten anyone. iii TABLE OF CONTENTS Dedications and Acknowledgements iii Table of Contents(More)
  • Ian A Cook, Andrew F Leuchter, Melinda L Morgan, Elise Witte Conlee, Steven David, Robert Lufkin +14 others
  • 2002
CONTEXT Healthy elderly persons commonly show 4 types of change in brain structure-cortical atrophy, central atrophy, deep white-matter hyperintensities, and periventricular hyperintensities-as forms of subclinical structural brain disease (SSBD). OBJECTIVES To characterize the volumes of SSBD present with aging and to determine the associations of SSBD,(More)
  • John P Roche, William Timberlake, Christie, Alain Giraldeau, Peter Bednekoff, Daniel Wiegmann +1 other
  • 2007
A number of studies have observed that animals experiencing positive energy budgets tend to prefer alternatives offering constant amounts of food over those offering variable amounts of food, i.e. they tend to be risk averse. This observation, and the related finding that small animals experiencing negative energy budgets have been observed to prefer(More)