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Children's hospitals have been excluded from the Medicare prospective payment system (PPS) because of concerns over the applicability of the DRG case-mix system and PPS payment weights to pediatric hospitalization. Nevertheless, DRG-based payment systems are being adopted by State Medicaid agencies and private third-party payers, and the Health Care(More)
BACKGROUND The patient-centered medical home (PCMH) has become a widely cited solution to the deficiencies in primary care delivery in the United States. To achieve the magnitude of change being called for in primary care, quality improvement interventions must focus on whole-system redesign, and not just isolated parts of medical practices. METHODS(More)
Objectives: Patient safety is an important national issue. To date, there has been little attention paid to patient safety in rural hospitals, which make up nearly half of all U.S. hospitals. Information is needed to target interventions for improving patient safety. Our objective was to determine how patient safety rates, offered services, and patient mix(More)
Important biomedical information is often recorded, published or archived in unstructured and semi-structured textual form. Artificial intelligence and knowledge discovery techniques may be applied to large volumes of such data to identify and extract useful metadata, not only for providing access to these documents, but also for conducting analyses and(More)
Pediatric-modified diagnosis-related groups (PM-DRGs) were designed to describe more accurately than DRGs differences in severity of illness and charges across pediatric patients. We report on an evaluation of PM-DRGs for use in prospective payment systems (PPSs). Data on pediatric discharges (i.e., patients 17 years of age or under) from 5 States and a(More)
To determine the extent of inappropriate hospital use, and to investigate factors related to variations in appropriateness, 8,031 hospital records of patients discharged from 41 hospitals in 3 Massachusetts professional standards review organization (PSRO) areas were reviewed in 1973 and 1978. The Appropriateness Evaluation Protocol (AEP) was used for the(More)
Equine infectious anemia virus (EIAV) causes lifelong infections ranging from acutely fatal, to chronic, to asymptomatic. Within infected animals, EIAV is found as a quasispecies. Many experimental studies on EIAV, carried out in the U.S. over the past 70 years, have used either the highly virulent Wyoming (EIAVwyo) field strain or various derivatives of(More)
Epilepsy is a debilitating disease characterized by recurring seizures. Epilepsy can be studied using animal models, such as rodents prone to audiogenic seizure (AGS), which experience generalized seizures (loss of consciousness accompanied by rhythmic muscle spasms and rigid muscle stiffness) after intense sound stimulation. In 1933, a spontaneous mutation(More)
OBJECTIVE Increasing uptake of cancer screening is a priority for health systems internationally, however, some patients may not attend because they are undergoing active treatment for the cancer of interest or have other medical reasons that mean participation would be inappropriate. This study aims to quantify the proportion of non-participants who have a(More)
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