Susan M Grimes

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Four treatment regimens for patients with specified combinations of low back pain and sciatica were evaluated. The largest group studied had low back pain with limited straight-leg raising (SLR) and in them the beneficial effect of manipulation in hastening pain relief was highly significant. In similar patients without limitation of SLR, the effect was of(More)
In mixed industrial effluent the presence of metal ions can retard the destruction of organic contaminants and the efficiency of recovery of the metal is reduced by the presence of the organic species. Results are presented for copper-2,4-dichlorophenoxyacetic acid (2,4-D) system in which both effects occur. An electrochemical cell alone can be used to(More)
A double-blind, placebo-controlled, cross-over trial of nifedipine 10 mg three times daily for 6 weeks, in 10 patients with Raynaud's phenomenon secondary to systemic sclerosis, is reported. A significant reduction in the duration of attacks of Raynaud's phenomenon was observed. Nifedipine therapy also reduced the number and severity of attacks of Raynaud's(More)
A photoreactor was developed to study products of photochemical oxidation in a wide range of organic compounds. Analysis of the products from the reactor were used to determine the extent of mineralization of the organic material, to characterize any intermediate compounds formed, and to obtain information on the decomposition mechanism. Appropriate methods(More)
In mixed wastewater streams, the presence of metal ions can retard the destruction of organic contaminants and the efficiency of recovery of the metal is reduced by the presence of organic species. The reduction in the efficiency of these methods is due to the formation of complexes between the organic species and the metal ions in solution. Results are(More)
Quantitative studies of the catalysed degradation of aqueous solutions of cinnamic 1, dihydrocinnamic 2, trans-caffeic 3 and dihydrocaffeic 4 acids in the presence of TiO2 and UV radiation at pH 3 and 10 are reported. The phenolic and aliphatic unsaturated groups in caffeic acid 3 caused it to be adsorbed more strongly than the phenolic saturated acid 4,(More)
Catalysed degradation of aqueous solutions of cinnamic 1, dihydrocinnamic 2, dihydrocaffeic 3 and trans-caffeic 4 acids in the presence of (TiO2) and UV radiation and the products identified by HPLC, and after treatment with diazomethane by GC-MS have been studied. A pH range of 3 to 11 was used. The four acids, in the presence of TiO2 in the dark,(More)
Ten patients with moderate to severe Raynaud’s syndrome were recruited into a four week randomised double blind crossover study to compare the efficacy of UK-38,485 50 mg, a new thromboxane synthetase inhibitor with that of placebo. With the doses used there was no significant difference between the two treatment periods in the number, severity and duration(More)
A fast and accurate analytical method, which uses commercially available adsorbents (Tenax TA, Carbotrap B and C, and Carbosieve S-III), was developed for the sampling and determination of aromatic hydrocarbons, chloroaromatic compounds, and 2,3,7,8-tetrachlorodibenzo-p-dioxin. The breakthrough volume data show that Carbotrap C has a good capacity for(More)