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BindN: a web-based tool for efficient prediction of DNA and RNA binding sites in amino acid sequences
TLDR
BindN provides a useful tool for understanding the function of DNA and RNA-binding proteins based on primary sequence data and the SVM models appear to be more accurate and more efficient for online predictions. Expand
Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp.
TLDR
A novel multiplex polymerase chain reaction (PCR) assay able to detect and distinguish alleles encoding three subgroups of acquired OXA carbapenemases that are scattered in Acinetobacter spp. Expand
The genome of the model beetle and pest Tribolium castaneum
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agriculturalExpand
A pair-rule gene circuit defines segments sequentially in the short-germ insect Tribolium castaneum.
TLDR
The periodicity of the Tribolium pair-rule gene interactions reveals components of the genetic hierarchy that are regulated in a repetitive circuit or clock-like mechanism that may be more generally applicable to segmentation in other arthropods. Expand
THE GUINEA PIG
With the solution of the immediate problems of the numerical phenomena of heredity and of the organization of hereditary units in the cell, the center of interest in genetics is tending to shiftExpand
Multiple Wnt Genes Are Required for Segmentation in the Short-Germ Embryo of Tribolium castaneum
TLDR
First evidence of functional redundancy between Wnt ligands in posterior patterning in short-germ insects is found, suggesting that Tc-porc is essential for the function of both ligands, which signal through the canonical pathway. Expand
Conservation, loss, and redeployment of Wnt ligands in protostomes: implications for understanding the evolution of segment formation
TLDR
Despite frequent losses of Wnt gene subfamilies in lineages such as insects, nematodes and leeches, most protostomes have probably maintained much of their ancestral repertoire of twelve Wnt genes. Expand
Insights into social insects from the genome of the honeybee Apis mellifera
TLDR
The genome sequence of the honeybee Apis mellifera is reported, suggesting a novel African origin for the species A. melliferA and insights into whether Africanized bees spread throughout the New World via hybridization or displacement. Expand
Dissecting Systemic RNA Interference in the Red Flour Beetle Tribolium castaneum: Parameters Affecting the Efficiency of RNAi
TLDR
The data provided here show that the concentration and length of dsRNA have profound effects on the efficacy of the RNAi response both in regard to initial efficiency and duration of the effect in Tribolium castaneum, and demonstrate that competitive inhibition ofdsRNA can occur when multiple dsRNAs are injected together, influencing the effectiveness of RNAi. Expand
FGKA: a Fast Genetic K-means Clustering Algorithm
TLDR
Experiments indicate that, while K-means algorithm might converge to a local optimum, both FGKA and GKA always converge to the global optimum eventually but FGKA runs much faster than GKA. Expand
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