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  • Ellis J Powell, Sara E. Charley, +12 authors Christopher K. Tuggle
  • Biology, Medicine
  • Laboratory animals
  • 2018 (First Publication: 1 August 2018)
  • Severe combined immunodeficiency (SCID) is defined by the lack of an adaptive immune system. Mutations causing SCID are found naturally in humans, mice, horses, dogs, and recently in pigs, with theContinue Reading
  • Maris Vilums, Annelien J M Zweemer, +7 authors Adriaan P. IJzerman
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2014 (First Publication: 1 December 2014)
  • A novel N-(2-oxo-2-(piperidin-4-ylamino)ethyl)-3-(trifluoromethyl)benzamide series of human CCR2 chemokine receptor antagonists was identified. With a pharmacophore model based on known CCR2Continue Reading