Susan C. Bolge

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OBJECTIVE This multinational, Internet-based survey was designed to assess the prevalence, frequency, severity, and impact of opioid-induced bowel dysfunction (OBD) in patients receiving opioid therapy for chronic pain and taking laxatives. DESIGN In total, 322 patients taking daily oral opioids and laxatives completed the 45-item questionnaire. At the(More)
OBJECTIVE To quantify the burden of uterine fibroids (UF) on health-related quality of life (HRQOL) and work productivity in a general population of women. STUDY DESIGN Women diagnosed with or experiencing UF-related symptoms living in five Western European countries (France, Germany, Italy, Spain, and the United Kingdom) were identified through a(More)
The objectives of this article were to estimate the prevalence of asthma control and describe the characteristics of at least well-controlled (ALWC) versus not well-controlled (NWC) asthmatics. Data were obtained from the European National Health and Wellness Survey, an internet-based, cross-sectional study of 37,476 adults in France, Germany, Italy, Spain(More)
To assess the association of insomnia with health-related quality of life (HRQOL), work productivity, and activity impairment. Data were obtained from the 2005 US National Health and Wellness Survey. Subjects were assigned to the insomnia group (diagnosed insomnia experienced at least a few times a month) or the noninsomnia group (no insomnia or sleep(More)
BACKGROUND Adherence to therapy is a key requirement underlying achievement of clinical outcomes in randomized controlled drug registration trials. In postmarketing studies, comparison of adherence among therapies can become more complicated when drug dosing and administration schedules differ or when methods used to measure adherence are not consistently(More)
OBJECTIVES To determine the effect of lower urinary tract symptoms, including overactive bladder/urinary incontinence, on health outcomes. METHODS Data were obtained from the 2006 U.S. National Health and Wellness Survey. Cases (those who reported experiencing a sudden overwhelming urge to urinate, a frequent urge to urinate, or urinating >8 times/d) were(More)
OBJECTIVE The study was conducted to examine the influence of demographics, health-related quality of life (HRQL) and duration of use on satisfaction with the transdermal contraceptive patch or oral contraceptives (OCs). METHODS In this cross-sectional analysis of the 2004 National Health and Wellness Survey (NHWS), women were currently using the patch(More)
BACKGROUND According to prescribing information for rheumatoid arthritis (RA) treatments in the United States, infliximab should be administered at weeks 1, 2, 6, and then every 8 weeks starting at a 3-mg/kg dose, with flexible dosing up to 10 mg/kg and/or every 4 weeks based on clinical response. OBJECTIVE This study evaluated dosing and intervals of the(More)
BACKGROUND Analysis of the burden of gastro-oesophageal reflux disease (GERD) in relation to the severity and frequency of symptoms is essential to identify individuals and groups in whom targeted management is justified. AIM To describe the relationship between symptoms of GERD and self-reported health-related quality of life (HRQL), work productivity,(More)
  • Susan C. Bolge, Heidi Waters, Catherine Tak Piech
  • Clinical therapeutics
  • 2010
OBJECTIVES The purpose of this study was to better understand the characteristics and patterns of treatment of flares of ulcerative colitis (UC) from the patient's perspective. A secondary objective was to determine the predictive value of disease characteristics, particularly disease flares, on current use of biologic therapy. METHODS Study participants(More)