Suror Alam

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The effects of the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) and the NO donor sodium nitroprusside (SNP) on whole body O2 consumption (VO2) were assessed in 16 dogs anesthetized with fentanyl or isoflurane. Cardiac output (CO) and mean arterial pressure (MAP) were measured with standard methods and were used to calculate VO2 and(More)
BACKGROUND An extracorporeal system was used to investigate the direct coronary vasomotor effects of sevoflurane and desflurane in vivo. The role of the adenosine triphosphate-sensitive potassium channels (KATP channels) in these effects was evaluated. METHODS Twenty-one open-chest, anesthetized (fentanyl-midazolam) dogs were studied. The left anterior(More)
Despite intensive investigation, the role of nitric oxide (NO) in cholinergic modulation of myocardial contractility remains unresolved. The left anterior descending coronary artery of 34 anesthetized, open-chest dogs was perfused via an extracorporeal circuit. Segmental shortening (SS) was measured with ultrasonic crystals and coronary blood flow (CBF) was(More)
Summary: The effects of chronic uremia on the intestinal transport of amino acids and glucose were assessed by an in vivo perfusion technique in young uremic rats and pair-fed controls. The experimental rats were rendered uremic by a modification of the conventional nephrectomy, and control animals were sham operated. All intestinal perfusions were(More)
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