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Transcriptomic analysis of the hippocampus from six inbred strains of mice suggests a basis for sex‐specific susceptibility and severity of neurological disorders
Identifying sex differences in gene expression within the brain is critical for determining why multiple neurological and behavioral disorders differentially affect males and females. SeveralExpand
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Efficient Projection onto the Perfect Phylogeny Model
TLDR
We use Moreau's decomposition for proximal operators, and a tree reduction scheme, to develop a new algorithm to compute the perfect phylogeny model to infer evolutionary trees. Expand
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An Examination of Dynamic Gene Expression Changes in the Mouse Brain During Pregnancy and the Postpartum Period
The developmental transition to motherhood requires gene expression changes that alter the brain to drive the female to perform maternal behaviors. We broadly examined the global transcriptionalExpand
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On the Complexity of the Weighted Fused Lasso
TLDR
In this letter, we prove that the number of segments in the solution path of the weighted fused lasso is <inline-formula><tex-math notation="LaTeX">$\mathcal {O}(n^2)$</ tex-math></inline- formula>, and that, for some instances, it is $\Omega (3^n)$. Expand
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The Drosophila Post-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions
Examining cross-tissue interactions is important for understanding physiology and homeostasis. In animals, the female gonad produces signaling molecules that act distally. We examine gene expressionExpand
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mRNA profiling reveals significant transcriptional differences between a multipotent progenitor and its differentiated sister
BackgroundThe two Caenorhabditis elegans somatic gonadal precursors (SGPs) are multipotent progenitors that generate all somatic tissues of the adult reproductive system. The sister cells of the SGPsExpand
Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior
Examining the role of chromatin modifications and gene expression in neurons is critical for understanding how the potential for behaviors are established and maintained. We investigate this questionExpand
Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior.
Examining the role of chromatin modifications and gene expression in neurons is critical for understanding how the potential for behaviors are established and maintained. We investigate this questionExpand
Exact inference under the perfect phylogeny model
TLDR
We use a careful combination of algorithms, software, and hardware, to develop EXACT: a tool that can explore the space of all possible phylogenetic trees, and performs exact inference under the PPM with noisy data. Expand
On the Complexity of the Weighted Fussed Lasso
TLDR
We prove that the number of segments in the solution path of the weighted fused lasso is O(n), and for some instances Ω(n). Expand