Sureshkumar Kalyanam

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Ultrasonic elasticity imaging enables visualization of soft tissue deformation for medical diagnosis. Our aim is to understand the role of flow-dependent and flow-independent viscoelastic mechanisms in the response of biphasic polymeric media, including biological tissues and hydrogels, to low-frequency forces. Combining the results of confined and(More)
The viscoelastic response of hydropolymers, which include glandular breast tissues, may be accurately characterized for some applications with as few as 3 rheological parameters by applying the Kelvin-Voigt fractional derivative (KVFD) modeling approach. We describe a technique for ultrasonic imaging of KVFD parameters in media undergoing unconfined,(More)
Elasticity imaging is emerging as an important tool for breast cancer detection and monitoring of treatment. Viscoelastic contrast in lesions is generated by disease specific processes that modify the molecular structure of connective tissues. We showed previously that gelatin hydrogels exhibit mechanical behavior similar to native collagen found in breast(More)
Mechanical properties of soft biological materials are dependent on the responses of the two phases of which they are comprised: the solid matrix and interstitial fluid. Indentation techniques are commonly used to measure properties of such materials, but comparisons between different experimental and analytical techniques can be difficult. Most models(More)
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