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- Sun-Mi Woo, Janghwan Kim, +6 authors Yong-Kook Kang
- BMC Neuroscience
- 2008
BackgroundStudies have provided important findings about the roles of Notch signaling in neural development. Unfortunately, however, most of these studies have investigated the neural stem cells… (More)
- Sunwha Cho, Jung sun Park, Yong-Kook Kang
- The Journal of biological chemistry
- 2011
Setdb1/Eset is a histone H3 lysine 9 (H3K9)-specific methyltransferase that associates with various transcription factors to regulate gene expression via chromatin remodeling. Here, we report that… (More)
- Young Sun Jeong, Sunwha Cho, Jung sun Park, Yong Deuk Ko, Yong-Kook Kang
- Genes to cells : devoted to molecular & cellular…
- 2010
Post-translational modifications of histones play important roles in regulating chromatin dynamics and epigenetic inheritance during mitosis. The epigenetic significance and stability of histone… (More)
- Sunwha Cho, Jung sun Park, Sujin Kwon, Yong-Kook Kang
- Gene expression patterns : GEP
- 2012
Setdb1/Eset, a histone lysine methyltransferase, is recruited by various transcription factors to modify local chromatin. The observation that Setdb1-null blastocysts fail to produce epiblast-lineage… (More)
- Sunwha Cho, Jung sun Park, Yong-Kook Kang
- Nucleic acids research
- 2014
In mammals, RNA interference is primarily a post-transcriptional mechanism. Evidence has accumulated for additional role in transcriptional gene silencing (TGS) but the question for a good paradigm… (More)
- Sunwha Cho, Jung sun Park, Yong-Kook Kang
- Genes to cells : devoted to molecular & cellular…
- 2013
Setdb1 is a histone H3-lysine 9 (H3K9)-specific methyltransferase that interacts with various transcriptional regulators to induce local heterochromatin formation and participates as an indispensable… (More)
Reprogramming incompletely occurs in most somatic cell nuclear transfer (SCNT) embryos, which results in misregulation of developmentally important genes and subsequent embryonic malfunction and… (More)
- Jung sun Park, Doosoo Lee, Sunwha Cho, Sang-Tae Shin, Yong-Kook Kang
- The International journal of developmental…
- 2010
Early mammalian embryos are thought to gain nuclear totipotency through DNA methylation reprogramming (DMR). By this process, DNA methylation patterns acquired during gametogenesis that are… (More)
- Kwang Bo Jung, Hana Lee, +13 authors Mi-Young Son
- Nature Communications
- 2018
Human pluripotent stem cell (hPSC)-derived intestinal organoids (hIOs) form 3D structures organized into crypt and villus domains, making them an excellent in vitro model system for studying human… (More)
- Jea-Woon Ryu, Seon-Kyu Kim, +8 authors Hyun-Soo Cho
- Oncotarget
- 2017
Hepatocellular carcinoma (HCC) is a major type of liver cancer caused by the hepatitis B and C viruses, alcohol and exposure to aflatoxin. For HCC treatment, anticancer drugs have been widely used,… (More)