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HEMATOPOIESIS AND STEM CELLS Runx1 and Cbfb regulate the development of Flt3 dendritic cell progenitors and restrict myeloproliferative disorder

• Ansuman T Satpathy, Carlos G. Briseño, +6 authors Takeshi Egawa
• 2014

Diversified subsets of mature blood cells develop from hematopoietic stem cells (HSCs) via intermediate progenitor populations with limited self-renewal and lineage potential. HSCs are enriched in… (More)

Runx1 and Cbfb regulate the development of Flt3 dendritic cell progenitors and restrict myeloproliferative disorder

• Ansuman T Satpathy, Carlos G. Briseño, +6 authors Takeshi Egawa
• 2014

Diversified subsets of mature blood cells develop from hematopoietic stem cells (HSCs) via intermediate progenitor populations with limited self-renewal and lineage potential. HSCs are enriched in… (More)

Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.

• Ansuman T Satpathy, Carlos G. Briseño, +6 authors Takeshi Egawa
• Blood
• 2014

Runx1 and Cbfβ are critical for the establishment of definitive hematopoiesis and are implicated in leukemic transformation. Despite the absolute requirements for these factors in the development of… (More)

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